죽염, 후박 및 센텔라 추출물을 배합한 구강양치액의 치면세균막 억제 및 치은염 감소 효과
Comparative effects of aqueous single-phase and oil-water two-phase mouthrinses containing bamboo salt, magnolia bark and Centella asiatica extracts on reducing gingivitis: a randomized clinical trial
최승재, 백대일, 진보형,
소속 상세정보
최승재 ( Choi Seung-Jae ) - 서울대학교 치의학대학원 예방치학교실
백대일 ( Paik Dai-Il ) - 서울대학교 치의학대학원 예방치학교실
진보형 ( Jin Bo-Hyoung ) - 서울대학교 치의학대학원 예방치학교실
Abstract
Objectives: The aim of this study was to assess the antiplaque and antigingivitis effectiveness of aqueous single-phase and oil-water two-phase mouthrinses, containing bamboo salt, magnolia bark, and Centella asiatica extracts, in Korean adults.
Methods: In this double-blinded clinical trial, a total of thirty-four participants aged over 19 years were randomly allocated to three experimental groups: 1) control group; 2) aqueous single-phase mouthrinse (ASM) group, and; 3) oil-water two-phase mouthrinse (OTM) group. The experimental mouthrinses all contained sodium fluoride, and the ASM and OTM contained additional ingredients of bamboo salt, magnolia bark, and Centella asiatica extracts. For the OTM, 50% essential oil was added to create an oil-water two-phase mouthrinse. A two-week randomized crossover design with a two-week washout period was applied. Following a complete dental prophylaxis, participants were instructed to use the prescribed mouthrinse twice daily for two weeks as an adjunct to their usual mechanical oral hygiene procedures. Pre- and post-experiment clinical examinations were performed to measure the plaque index (PI) and bleeding on probing (BOP) for the full mouth. Paired t-test was applied to compare the intergroup differences for all clinical variables.
Results: Compared to the control group, ASM showed a significantly reduced BOP (P<0.05). However, there was no statistically significant difference in the effects of the three mouthrinses on reducing the PI.
Conclusions: The results of this study indicate that the use of an aqueous, single-phase mouthrinse containing bamboo salt, magnolia bark and Centella asiatica extracts could help alleviate gingivitis.
키워드
Bamboo salt; Centella asiatica; gingivitis; magnolia bark; mouthrinse
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